Class III Treatment Research Earns Dental Student IADR Award

Dentistry Today


Pegah Khosravi-Kamrani has won the International Association for Dental Research (IADR) 2020 Junior Craniofacial Biology Award. The University of North Carolina Adams School of Dentistry student was one of 10 finalists selected from research abstracts submitted to IADR from around the world.

“I’m thrilled to have been recognized at the national level for my project,” said Khosravi-Kamrani, who developed her research, “Categorizing Cl III Subtypes, Treatment Modes, and Treatment Outcomes” is part of an ongoing Class III research program that originated in the lab of Sylvia Frazier-Bowers, DDS, PhD.

“This award was a team effort and would not have been possible without Dr. Frazier-Bowers for her mentorship, Dr. Wiesen for his collaboration, as well as Dr. Wright and Dr. Slade for their feedback on my presentation,” she said. “This award represents the appealing translational dimension of our research and affirms my commitment to research throughout my career.”

Previous research at the Frazier-Bowers lab identified five predominant subtypes of the Class III malocclusion and created a mathematical model that assigns a subtype to any given patient using their cephalometric measurements.

Khosravi-Kamrani’s project looked at orthodontic records of Class III patients, using the mathematical model to assign their subtype, and retrospectively determined whether one subtype was at higher risk for orthnognathic surgery, including treatment failure.

“The model I utilized has the potential to improve the diagnostic process of Cl III patients, in turn allowing for better prediction of treatment outcomes,” said Khosravi-Kamrani. “This is particularly encouraging as Class III diagnosis, prognosis, and treatment have continually been challenges for orthodontists.”

“We are quickly moving toward a time where machine learning or artificial intelligence will influence our decisions, clinical and otherwise,” said Frazier-Bowers, an associate professor in the Department of Orthodontics.

“While the mathematical model is not ready for immediate real-time application yet, these findings promise to stimulate that possibility in the coming years. I am grateful to Pegah for her diligence, dedication, and intellect that helped fuel this award-winning outcome,” Frazier-Bowers said.

Abstracts are judged for originality and scientific design of the investigation, suitability of the methods of analysis, and scientific value of the work. The Junior Craniofacial Biology Award recognizes original and outstanding research in craniofacial growth and development. It is sponsored by DENTAID and the membership of the IADR Craniofacial Biology Group.

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