Arestin Significantly Reduces Bacteria Responsible for Periodontal Disease

Dentistry Today


A new study highlighting the antimicrobial effectiveness of Arestin (minocycline hydrochloride) 1-mg microspheres in the treatment of periodontal disease was presented at the first joint annual session of the American Dental Education Association (ADEA) and the American Association of Dental Research (AADR) from March 8 to 11, 2006, in Orlando, Fla. The study reveals a significant reduction in Red Complex Bacteria (RCB) among patients with periodontal disease who were treated with Arestin plus scaling and root planing (SRP) compared with patients who were treated with SRP alone. In addition, the study shows that Arestin plus SRP is more effective than SRP alone in reducing periodontal pocket depth and bleeding on probing (including smokers) and increasing clinical attachment. Red Complex Bacteria includes 3 pathogens associated with microbial infection in people with periodontal disease: Porphyromonas gingivalis, Tannerella forsythensis, and Treponema denticola.


(Source: Lanmark Group news release, March 30, 2006)