Some Oral Bacteria Pave Way for Others

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Some bacteria may make people susceptible to many others.

Fusobacterium nucleatum enables other bacteria, such as Eserichia coli to enter a person’s body through the bloodstream, resulting in illness, according to a research team at Case Western University. Yiping Ham, professor of periodontics at Case Western Reserve School of Dental Medicine, made the finding after analyzing Fusobacterium nucleatum, which is some of the most common bacteria present in the mouth.

This bacteria has a type of bonding agent that breaks the junctures of the interlocking sheath of endothelial cells, which is the way the bacteria enables a path for other bacteria to enter the blood.

It’s been determined that there’s a correlation between this oral bacteria and preterm death and fetal death. This bacteria has also been associated with other infections and abscesses in the lungs, liver, brain, spleen and joints.

After pinpointing and genetically matching the bacteria in the case of fetal death, Han began to realize how an oral bacterium can be located throughout the body and manages to get through placental barriers. After entering the body due to an injury or periodontal disease, F. nucleatum is unique because it produces signals that allow it spread throughout the body.

To confirm the abilities of F. nucleatum, researchers introduced E. coli into a bond. Before F. nucleatum was present, the bond did not break simply from E. coli. After F. nucleatum was present, however, the bond broke because of E. coli.

After ending its ride through the bloodstream, F. nucleatum starts to colonize. That’s when the major illnesses and possible death result.