Oral Thrush Problematic for HIV Patients

Keeping up with one’s oral care is one of the forgotten aspects for treating patient with HIV. But oral candidiasis is a major issue for people whose immune systems are hampered in some way.

That’s why Case Western Reserve University conducted a comprehensive study on the matter. The information appears in the journal PLOS Pathogens.

The goal of the study was to examine the mouths of people who are HIV positive and compare them to people with healthy mouths. The bacteria were analyzed using high-throughput gene sequencing.

The bacteria were the same for both sides. Oral fungi, however, was distinct for people with HIV and healthy people.

The Candida family of fungi was much more prevalent among the HIV patients. Pichia was something seen in higher levels among the healthy people.

The theory was that one fungus had a way of suppressing the other. To test this theory, Pichia was grown in a liquid while the fungus was filtered out. The Pichia managed to stop Candida and other disease-causing fungi to stop growing. Therefore, it makes sense that oral thrush is often associated with the HIV infection.

The research was confirmed after tests on mice were conducted.