Industry News

Gene Removal Leads to Additional Teeth

Gene Removal Leads to Additional Teeth

26 June 2017

The FAM20B gene is necessary for cartilage development. But when it’s selectively removed in mouse...

eBooks

May 2017

The Dentist’s Guide
To Managing Employees

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April 2017

Composite Vs. Porcelain’s:
What You Need To Know

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March 2017

Digital Marketing for Dentists

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February 2017

Traumatic Dental Injuries: Emergency Assessment And Treatment

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Recent Issues

June 2017

Digital Technologies: Changing the Face of Dentistry




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May 2017

Solving Aesthetic Challenges From Trauma-Based Injuries




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New Drug May Aid in Oral Cancer Treatment

There could be a new method to treat mouth sores normally associated with cancer.

Mouse model studies have shown that protein Smad7, when given genetically or topically, could thwart the mouth sores that develop in cancer patients.

Mouth sores are a major problem for some cancer patients. They can become so severe that feeding tubes are necessary for nutrition and painkillers are later needed. Roughly 40 to 70 percent of patients with upper-body radiation encounter this problem. And, unfortunately for these patients, there is no known treatment as of now.

The study involving this new protein appears in Nature Medicine.

The group of researchers would like to further explore the possibilities of Smad7 as a way to combat human oral mucositis. In some of the studies, Smad7 was combined with a short peptide to permit the protein to cross through cell membranes. This was produced from cultured bacteria. After the substance was applied to the mouse’s oral cavity, it prevented oral mucositis, in addition to healing ulcers that were already present.

The ultimate goal from this research is to create a drug that can be given topically that will treat oral mucositis and deter more sores from developing.

The mice were engineered in a manner that they developed oral mucositis similar to the condition that human cancer patients are afflicted with. This made way for numerous tests and experiments.

The Wednesday Watch

Exclusive Interview: Patient Education and GentleWave

Exclusive Interview: Patient Education and GentleWave

21 June 2017

Patients are becoming more educated, as a world of information is readily available at our...

Technique of the Week

e-Prescribing with XLDent

e-Prescribing with XLDent

29 March 2017

Drs. David Andersen and Lora Nelson explain how easy e-Prescribing...

Technology Today

Show Me the Way

Show Me the Way

02 May 2017

This year’s International Dental Show did not disappoint: 155,000 participants from 157 countries attended,...

Implants Today

Narrow-Body  Dental Implants

Narrow-Body Dental Implants

02 May 2017

As the multibillion-dollar market for dental implants grows, many new companies are entering the...

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