Today's Dental News

Genetic Mutations Associated with Salivary Gland Tumors

A recent discovery could pave the way for better treatment of oral cancer.

The Scripps Research Institute found links involving a set of genes that promotes tumor growth and mucoepidermoid carcinoma, which is an oral cancer that impacts the salivary glands. This finding may lead to new treatment that could pinpoint the genetic causes of this type of cancer.

The information appears in Proceedings of the National Academy of Sciences.

The researchers determined that a pair of proteins—known as CRTC1/MAML2—that are joined together by genetic mutation result in the growth and spread of oral cancer.

Read more: Genetic Mutations Associated with Salivary Gland Tumors

 

Anti-Pain Agent Reduces Oral Cancer, Leaves Healthy Tissue Unharmed

There may be a new way to treat oral cancer.

Mouse models of human oral cancer were treated with something called capsazepine, which simultaneously resulted in tumor shrinkage while sparing surrounding tissue. Researchers from the School of Dentistry and School of Medicine at The University of Texas Health Science Center at San Antonio conducted the study. The information appears in Oral Oncology.

Oral squamous cell carcinoma ranks eighth on the list of most common forms of cancer in the United States. There are roughly 40,000 new cases and 8,000 deaths each year.

Read more: Anti-Pain Agent Reduces Oral Cancer, Leaves Healthy Tissue Unharmed

   

Some Healthy Treats may be Harmful

Healthy treats may not be what they claim to be.

Many treats that profess to be healthy options to consider instead of sweets or chocolate may, in fact, contain excessive amount of sugar or high acidity levels. Some studies even show that raisins or cereal bars and drinks like smoothies or fruit juices can be as damaging to teeth as soda.

There are cases all the time of children who end up with some type of tooth decay even though the child’s parents took measures to prevent such a thing from happening.

The problems often stem from enamel damage caused by the food or drinks that prove to be unexpectedly high in sugar or acidity.

Read more: Some Healthy Treats may be Harmful

   

Anti-Arthritis Drugs May Worsen Other Inflammatory Diseases

Some anti-arthritis drugs may be counterproductive.

New studies show that there are some anti-arthritis drugs that may actually exacerbate inflammatory diseases. A study in the American Journal of Pathology spotlights the impact of anti-arthritic drugs.

More than 60 years ago, adrenocorticotropic hormone was proven to be successful in treating rheumatoid and gouty arthritis. But now it is rarely used. Researchers now value the idea that the anti-inflammatory actions of ACTH are mediated through the peripheral melanocortin system on MC receptors that are shown in bone cells, immune cells and fibroblasts.

Read more: Anti-Arthritis Drugs May Worsen Other Inflammatory Diseases

   

Tooth Protein May Lead to Bone Regeneration

A newly discovered protein may lead to numerous health benefits.

Bioengineers at Queen Mary University of London found a protein that may aid patients suffering from osteoporosis or bone fractures. The protein statherin, which is usually found in the formation of enamel, can actually lead to bone growth.

The information appears in the journal Biomaterials.

The research team generated bioactive membranes from segments of different proteins to demonstrate which protein played the role in stimulating bone growth. The bone-stimulating aspect of the protein was tested in a rat model. The researchers employed analytical techniques to visualize and measure the calcified tissue.

Read more: Tooth Protein May Lead to Bone Regeneration

   

Page 1 of 161