Science and Medicine

Jet Lagged? Time to Reset That Inner Clock

Identifying the structure of dCRY is a starting point to understand the function and mechanisms of the protein.

A better understanding of how circadian rhythms work could lead to better treatments for jet lag and perhaps even more serious syndromes, a new study shows.

Researchers have identified for the first time the 3-D crystal structure of a protein in fruit flies (Drosophila) that also facilitates circadian rhythm functions in most higher organisms—from cyanobacteria and plants to animals, including humans.

While the mechanisms of circadian—or biological—clocks are complex in humans, many of their key components are shared by such lower species as Drosophila, which serve as a model organism for understanding circadian rhythms.

The study reported in the journal Nature identifies a protein called cryptochrome (dCRY) that plays a key role in circadian clocks, which get cues from daylight and allow organisms to pace their metabolism on a 24-hour cycle.

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Rising Air Pollution Worsens Drought, Flooding, New Study Finds

Our findings have significant policy implications for sustainable development and water resources, especially for those developing regions susceptible to extreme events such as drought and flood.

Increases in air pollution and other particulate matter in the atmosphere can strongly affect cloud development in ways that reduce precipitation in dry regions or seasons, while increasing rain, snowfall and the intensity of severe storms in wet regions or seasons, says a new study by a University of Maryland-led team of researchers.

The research provides the first clear evidence of how aerosols—soot, dust and other small particles in the atmosphere—can affect weather and climate; and the findings have important implications for the availability, management and use of water resources in regions across the United States and around the world, say the researchers and other scientists.

“Using a 10-year dataset of extensive atmosphere measurements from the U.S. Southern Great Plains research facility in Oklahoma [run by the Department of Energy’s Atmospheric Radiation Measurement program]—we have uncovered, for the first time, the long-term, net impact of aerosols on cloud height and thickness, and the resultant changes in precipitation frequency and intensity,” said Zhanqing Li, a professor of atmospheric and oceanic science at Maryland and lead author of the study.

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Greenhouse Gas Index Continues to Climb

Scientists at NOAA’s Earth System Research Laboratory prepare the AGGI each year from atmospheric data collected through an international cooperative air sampling network of more than 100 sites around the world.

NOAA’s updated Annual Greenhouse Gas Index, which measures the direct climate influence of many greenhouse gases such as carbon dioxide and methane, shows a continued steady upward trend that began with the Industrial Revolution of the 1880s.

Started in 2004, the AGGI reached 1.29 in 2010. That means the combined heating effect of long-lived greenhouse gases added to the atmosphere by human activities has increased by 29 percent since 1990, the “index” year used as a baseline for comparison. This is slightly higher than the 2009 AGGI, which was 1.27, when the combined heating effect of those additional greenhouse gases was 27 percent higher than in 1990.

“The increasing amounts of long-lived greenhouse gases in our atmosphere indicate that climate change is an issue society will be dealing with for a long time,” said Jim Butler, director of the Global Monitoring Division of NOAA’s Earth System Research Laboratory in Boulder, Colo. “Climate warming has the potential to affect most aspects of society, including water supplies, agriculture, ecosystems and economies. NOAA will continue to monitor these gases into the future to further understand the impacts on our planet.”

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