Antimicrobial Photodynamic Therapy for Periodontitis

Investigating changes occurring in the sub­gingival microbiological composition of subjects with aggressive periodontitis who were treated with antimicrobial photodynamic therapy (aPDT) in a single epi­sode, or scaling and root planing (SRP), this study by Dr. Arthur Novaes, et al used a split-mouth design on negative-7, zero, and plus-90 days. Ten patients were randomly as­­signed to either aPDT using a laser source in conjunction with a photosensitizer, or SRP with hand instruments. Sub­gingival plaque samples were collected and using checkerboard DNA-DNA hy­bridization determined counts of 40 subgingival species. The data were analyzed using the method of generalized estimating equations to test the associations be­tween treatments, evaluated parameters, and experimental times (α =  .05). The re­sults indicated that aPDT was more effective in lowering Aggregatibacter actinomy­cetem­co­mitans numbers; SRP was more efficient in reducing the presence of Red Com­plex periodontal pathogens. Within this trial, aPDT and SRP effects on different groups of bacteria suggest that their association may be beneficial for the nonsurgical treatment of aggressive periodontitis.
(Source: Lasers in Medical Science, accessed March 21, 2011)

Dentistry Today is The Nation's Leading Clinical News Magazine for Dentists. Here you can get the latest dental news from the whole world quickly.


Sponsor Logos